PeptideGuide UK
Recovery

BPC-157

Also known as: Body Protection Compound 157, PL 14736

RouteSubcutaneous
UK StatusNot a licensed medicine in the UK. Not a controlled substance under the Misuse of Drugs Act 1971. Legal to purchase for research purposes. Not approved for human use by the MHRA. Import for personal use exists in a legal grey area.

Overview

BPC-157 is a synthetic peptide derived from a protective protein found in gastric juice. It has attracted significant research interest for its remarkable tissue-healing and cytoprotective properties. The peptide consists of 15 amino acids and demonstrates stability in human gastric juice, making it a subject of study for gastrointestinal, musculoskeletal, and neurological repair.

Mechanism of Action

BPC-157 exerts its effects through multiple pathways. It upregulates growth hormone receptor expression, stimulates nitric oxide synthesis, modulates the dopaminergic and serotonergic systems, and promotes angiogenesis via VEGF signalling. It also activates the FAK-paxillin pathway involved in cell migration and wound healing. Its cytoprotective actions appear to be mediated partly through interaction with the NO system.

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Last reviewed: Reviewed by: [email protected]